cd4 t cell — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T12079	ML604440		Proteasome
	ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.		Proteasome
T30077	Anisperimus	LF 150195,LF-150195,LF 15-0195,LF-15-0195,LF15-0195	Caspase
	Anisperimus (LF 15-0195) is an immunosuppressant that enhances activation-induced T-cell death by promoting caspase-8 and caspase-10 activation at the DISC level, and prevents CNS autoimmunity by promoting the developmen...		Caspase
T5S0993	Kurarinone		BCL , Others , IκB/IKK , TNF , NF-κB , JAK , STAT
	Kurarinone, a flavanoid derived from shrub Sophora flavescens,Kurarinone exhibits anti-tumor, estrogenic, and anti-inflammatory activities, it also shows strong inhibitory effect on immune responses. Kurarinone may ameli...		BCL , Others , IκB/IKK , TNF , NF-κB , JAK , STAT
T81011	Tetanus Toxin (830–844)
	Tetanus Toxin (830–844), a biologically active peptide and a tetanus toxin-derived peptide TT830–844 CD4+ T-cell epitope, exhibits promiscuity by binding to a wide spectrum of HLA–DRB molecules. Consequently, it is antic...
T80744	Zanolimumab	Anti-Human CD4 Recombinant Antibody
	Zanolimumab (Anti-Human CD4 Recombinant Antibody) is a fully human monoclonal antibody that targets the CD4 molecule and effectively inhibits T-cell receptor (TCR) signal transduction. It is used in the research of rheum...
T72099	Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl
	Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl is an HIV-1 inhibitor that functions by interacting with gp120, thereby preventing its binding to CD4. This mechanism helps to maintain CD4-dependent T cell function.
T82179	HOXB7 8–25	MDM2 32-46
	HOXB7 8–25 (MDM2 32-46) is a peptide epitope derived from MDM2 that can induce both antigen-specific and tumor-reactive CD4+ T cell responses [1].
T77049	Keliximab
	Keliximab (SB-210396), a chimeric human/macaque IgG1 anti-CD4 monoclonal antibody, demonstrates a binding affinity for soluble CD4 with a K i value of 1.0 nM. It inhibits T cell proliferation and IL-2 production, making ...
T39863	LCMV GP (61-80)
	LCMV GP (61-80) is a peptide fragment derived from LCMV glycoprotein (GP) and corresponds to amino acids 61-80. This specific epitope, LCMV GP (61-80), has the ability to elicit CD4+ T-cell response.
T80621	Semzuvolimab	UB421
	Semzuvolimab, a murine IgG1κ antibody, targets the p55 T-cell surface antigen T4/Leu-3 (CD4). It has demonstrated capabilities to neutralize HIV infection and may inhibit HIV in patients on stable highly active antiretro...
T38687	Influenza Matrix Protein (61-72)
	Influenza Matrix Protein (61-72) is a peptide derived from the matrix protein of influenza viruses and encompasses amino acids 61-72. This specific epitope, Influenza Matrix Protein (61-72), has the ability to elicit a C...
TP2080	ADWX 1
	Potent and selective KV1.3 channel blocker (IC50 values are 0.0019 and 0.65 nM for KV1.3 and KV1.1, respectively). Inhibits CD4+ CCR7- T cell activation. Ameliorates rat experimental autoimmune encephalomyelitis, in a mo...
T78031	MOG peptide (35-55)
	MOG peptide (35-55), a myelin oligodendrocyte glycoprotein (MOG) fragment spanning amino acids 35 to 55, selectively stimulates CD4+ T cell expansion and induces experimental autoimmune encephalomyelitis (EAE) in animal ...
T72668	PD-1/PD-L1-IN-26		PD-1/PD-L1
	PD-1/PD-L1-IN-26 (Compound II-14) is a potent PD-1/PD-L1 inhibitor, demonstrating an IC50 of 0.0380 μM. It enhances the immune microenvironment by facilitating CD4+ T cell infiltration into tumor tissues, indicating pote...		PD-1/PD-L1
TP1703	FliC, Serotype a (427-441), S.paratyphi A
	This is amino acids 427 to 441 fragment belongs to the FliC, serotype a of the S. FliC epitope recognized by a CD4+ T cell from naturally infected C57BL/6 mice is located in a region common to a number of distinct Salmon...
T25109	ARN-6039	ARN 6039,ARN6039
	ARN-6039 is an orally available inverse agonist of RORγ for Autoimmune Neuroinflammatory Demyelinating Disease. The activity of ARN-6039 against RORγ was demonstrated in a RORγ-activated IL-17A Prom/LUCPorter assay in HE...
T83724	TPP-1 hydrochloride	Targeting PD-L1 Peptide
	TPP-1, a peptide inhibitor, targets the interaction between programmed cell death protein 1 (PD-1) and its ligand (PD-L1), binding specifically to PD-L1 with a dissociation constant (Kd) of 94.67 nM. At a concentration o...
T73651	Forigerimod TFA
	Forigerimod TFA (IPP-201101 TFA), a CD4 T-cell modulator, is a phosphorylated 21-amino-acid fragment derived from U1 small nuclear ribonucleoprotein 70 kDa, specifically at Ser140. It notably inhibits autophagy and is ut...
T83846	HOXB7 (8-25) TFA	Homeobox B7 (8-25)
	HOXB7 (8-25), a peptide fragment derived from homeobox B7 (HOXB7)—a key controller of cell growth and oncogene activator—facilitates antigen presentation when pulsed onto dendritic cells obtained from human peripheral bl...
T36034	CAY10774
	CAY10774 is an inhibitor of the protein-protein interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 (IC50= 15 nM in a homologous time-resolved fret (HTRF) assay).1It increases the activation of Jurkat...